The chips implanted inside the clone troopers could be activated by voice command, with Palpatine only needing to say 'Execute Order 66' to do so. The control chips were extremely effective at taking over the minds of those who had been implanted with them, erasing all existing biases and beliefs in the clone troopers to force them to eliminate the Jedi without question, even if the clones had loyally served under their Jedi General for years. However, after the Sith hijacked the project, the chips were tooled to another purpose: to force the clones to comply with the execution of Order 66, which wiped out nearly all Jedi. According to Doctor Nala Se, it was not uncommon for clones of many different kinds to be implanted with inhibitor chips.
They are totally obedient, taking any order without question.' ―Lama Su, to Jedi Knight Obi-Wan Kenobi īehavioral modification biochips were implanted in the clone troopers of the Grand Army of the Republic on the suggestion of Jedi Master Sifo-Dyas, who initially ordered the clone army, as a contingency against the clones being given orders by rogue Jedi.
' We modified their genetic structure to make them less independent than the original host.